"MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2."
Kozopas K.M. , Yang T. , Buchan H.L. , Zhou P. , Craig R.W.
Proc. Natl. Acad. Sci. U.S.A.90:3516-3520(1993) [PubMed] [Europe PMC] [Abstract]

"Induction of mcl1/EAT, Bcl-2 related gene, by retinoic acid or heat shock in the human embryonal carcinoma cells, NCR-G3."
Umezawa A. , Maruyama T. , Inazawa J. , Imai S. , Takano T. , Hata J.
Cell Struct. Funct.21:143-150(1996) [PubMed] [Europe PMC] [Abstract]

"Functional analysis of the human MCL-1 gene."
Akgul C. , Turner P.C. , White M.R.H. , Edwards S.W.
Cell. Mol. Life Sci.57:684-691(2000) [PubMed] [Europe PMC] [Abstract]

"Exon skipping in Mcl-1 results in a Bcl-2 homology domain 3 only gene product that promotes cell death."
Bingle C.D. , Craig R.W. , Swales B.M. , Singleton V. , Zhou P. , Whyte M.K.B.
J. Biol. Chem.275:22136-22146(2000) [PubMed] [Europe PMC] [Abstract]

"MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain."
Bae J. , Leo C.P. , Hsu S.Y. , Hsueh A.J.W.
J. Biol. Chem.275:25255-25261(2000) [PubMed] [Europe PMC] [Abstract]

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , Yamamoto J. , Saito K. , Kawai Y. , Isono Y. , Nakamura Y. , Nagahari K. , Murakami K. , Yasuda T. , Iwayanagi T. , Wagatsuma M. , Shiratori A. , Sudo H. , Hosoiri T. , Kaku Y. , Kodaira H. , Kondo H. , Sugawara M. , Takahashi M. , Kanda K. , Yokoi T. , Furuya T. , Kikkawa E. , Omura Y. , Abe K. , Kamihara K. , Katsuta N. , Sato K. , Tanikawa M. , Yamazaki M. , Ninomiya K. , Ishibashi T. , Yamashita H. , Murakawa K. , Fujimori K. , Tanai H. , Kimata M. , Watanabe M. , Hiraoka S. , Chiba Y. , Ishida S. , Ono Y. , Takiguchi S. , Watanabe S. , Yosida M. , Hotuta T. , Kusano J. , Kanehori K. , Takahashi-Fujii A. , Hara H. , Tanase T.-O. , Nomura Y. , Togiya S. , Komai F. , Hara R. , Takeuchi K. , Arita M. , Imose N. , Musashino K. , Yuuki H. , Oshima A. , Sasaki N. , Aotsuka S. , Yoshikawa Y. , Matsunawa H. , Ichihara T. , Shiohata N. , Sano S. , Moriya S. , Momiyama H. , Satoh N. , Takami S. , Terashima Y. , Suzuki O. , Nakagawa S. , Senoh A. , Mizoguchi H. , Goto Y. , Shimizu F. , Wakebe H. , Hishigaki H. , Watanabe T. , Sugiyama A. , Takemoto M. , Kawakami B. , Yamazaki M. , Watanabe K. , Kumagai A. , Itakura S. , Fukuzumi Y. , Fujimori Y. , Komiyama M. , Tashiro H. , Tanigami A. , Fujiwara T. , Ono T. , Yamada K. , Fujii Y. , Ozaki K. , Hirao M. , Ohmori Y. , Kawabata A. , Hikiji T. , Kobatake N. , Inagaki H. , Ikema Y. , Okamoto S. , Okitani R. , Kawakami T. , Noguchi S. , Itoh T. , Shigeta K. , Senba T. , Matsumura K. , Nakajima Y. , Mizuno T. , Morinaga M. , Sasaki M. , Togashi T. , Oyama M. , Hata H. , Watanabe M. , Komatsu T. , Mizushima-Sugano J. , Satoh T. , Shirai Y. , Takahashi Y. , Nakagawa K. , Okumura K. , Nagase T. , Nomura N. , Kikuchi H. , Masuho Y. , Yamashita R. , Nakai K. , Yada T. , Nakamura Y. , Ohara O. , Isogai T. , Sugano S. more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

NIEHS SNPs program
Submitted (2005-06) to the EMBL/GenBank/DDBJ databases

"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , Atkinson A. , Cooper R. , Jones C. , Hall R.E. , Andrews T.D. , Lloyd C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Anderson F. , Andrew R.W. , Ashwell R.I.S. , Aubin K. , Babbage A.K. , Bagguley C.L. , Bailey J. , Beasley H. , Bethel G. , Bird C.P. , Bray-Allen S. , Brown J.Y. , Brown A.J. , Buckley D. , Burton J. , Bye J. , Carder C. , Chapman J.C. , Clark S.Y. , Clarke G. , Clee C. , Cobley V. , Collier R.E. , Corby N. , Coville G.J. , Davies J. , Deadman R. , Dunn M. , Earthrowl M. , Ellington A.G. , Errington H. , Frankish A. , Frankland J. , French L. , Garner P. , Garnett J. , Gay L. , Ghori M.R.J. , Gibson R. , Gilby L.M. , Gillett W. , Glithero R.J. , Grafham D.V. , Griffiths C. , Griffiths-Jones S. , Grocock R. , Hammond S. , Harrison E.S.I. , Hart E. , Haugen E. , Heath P.D. , Holmes S. , Holt K. , Howden P.J. , Hunt A.R. , Hunt S.E. , Hunter G. , Isherwood J. , James R. , Johnson C. , Johnson D. , Joy A. , Kay M. , Kershaw J.K. , Kibukawa M. , Kimberley A.M. , King A. , Knights A.J. , Lad H. , Laird G. , Lawlor S. , Leongamornlert D.A. , Lloyd D.M. , Loveland J. , Lovell J. , Lush M.J. , Lyne R. , Martin S. , Mashreghi-Mohammadi M. , Matthews L. , Matthews N.S.W. , McLaren S. , Milne S. , Mistry S. , Moore M.J.F. , Nickerson T. , O'Dell C.N. , Oliver K. , Palmeiri A. , Palmer S.A. , Parker A. , Patel D. , Pearce A.V. , Peck A.I. , Pelan S. , Phelps K. , Phillimore B.J. , Plumb R. , Rajan J. , Raymond C. , Rouse G. , Saenphimmachak C. , Sehra H.K. , Sheridan E. , Shownkeen R. , Sims S. , Skuce C.D. , Smith M. , Steward C. , Subramanian S. , Sycamore N. , Tracey A. , Tromans A. , Van Helmond Z. , Wall M. , Wallis J.M. , White S. , Whitehead S.L. , Wilkinson J.E. , Willey D.L. , Williams H. , Wilming L. , Wray P.W. , Wu Z. , Coulson A. , Vaudin M. , Sulston J.E. , Durbin R.M. , Hubbard T. , Wooster R. , Dunham I. , Carter N.P. , McVean G. , Ross M.T. , Harrow J. , Olson M.V. , Beck S. , Rogers J. , Bentley D.R. more...
Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , Yooseph S. , Lu F. , Nusskern D.R. , Shue B.C. , Zheng X.H. , Zhong F. , Delcher A.L. , Huson D.H. , Kravitz S.A. , Mouchard L. , Reinert K. , Remington K.A. , Clark A.G. , Waterman M.S. , Eichler E.E. , Adams M.D. , Hunkapiller M.W. , Myers E.W. , Venter J.C. more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Acute myeloid leukemia possessing jumping translocation is related to highly elevated levels of EAT/mcl-1, a Bcl-2 related gene with anti-apoptotic functions."
Okita H. , Umezawa A. , Fukuma M. , Hata J.
Leuk. Res.24:73-77(2000) [PubMed] [Europe PMC] [Abstract]

"Mcl-1 is required for Akata6 B-lymphoma cell survival and is converted to a cell death molecule by efficient caspase-mediated cleavage."
Michels J. , O'Neill J.W. , Dallman C.L. , Mouzakiti A. , Habens F. , Brimmell M. , Zhang K.Y.J. , Craig R.W. , Marcusson E.G. , Johnson P.W.M. , Packham G.
Oncogene23:4818-4827(2004) [PubMed] [Europe PMC] [Abstract]

"Mcl-1 is an immediate-early gene activated by the granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling pathway and is one component of the GM-CSF viability response."
Chao J.-R. , Wang J.-M. , Lee S.-F. , Peng H.-W. , Lin Y.-H. , Chou C.-H. , Li J.-C. , Huang H.-M. , Chou C.-K. , Kuo M.-L. , Yen J.J.-Y. , Yang-Yen H.-F.
Mol. Cell. Biol.18:4883-4898(1998) [PubMed] [Europe PMC] [Abstract]

"Physical and functional interaction between myeloid cell leukemia 1 protein (MCL1) and fortilin. The potential role of MCL1 as a fortilin chaperone."
Zhang D. , Li F. , Weidner D. , Mnjoyan Z.H. , Fujise K.
J. Biol. Chem.277:37430-37438(2002) [PubMed] [Europe PMC] [Abstract]

"Phosphorylation and inactivation of myeloid cell leukemia 1 by JNK in response to oxidative stress."
Inoshita S. , Takeda K. , Hatai T. , Terada Y. , Sano M. , Hata J. , Umezawa A. , Ichijo H.
J. Biol. Chem.277:43730-43734(2002) [PubMed] [Europe PMC] [Abstract]

"Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex."
Leu J.I.-J. , Dumont P. , Hafey M. , Murphy M.E. , George D.L.
Nat. Cell Biol.6:443-450(2004) [PubMed] [Europe PMC] [Abstract]

"MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol."
Domina A.M. , Vrana J.A. , Gregory M.A. , Hann S.R. , Craig R.W.
Oncogene23:5301-5315(2004) [PubMed] [Europe PMC] [Abstract]

"Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis."
Zhong Q. , Gao W. , Du F. , Wang X.
Cell121:1085-1095(2005) [PubMed] [Europe PMC] [Abstract]

"Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1."
Maurer U. , Charvet C. , Wagman A.S. , Dejardin E. , Green D.R.
Mol. Cell21:749-760(2006) [PubMed] [Europe PMC] [Abstract]

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

"Serine 162, an essential residue for the mitochondrial localization, stability and anti-apoptotic function of Mcl-1."
Thomas L.W. , Lam C. , Clark R.E. , White M.R. , Spiller D.G. , Moots R.J. , Edwards S.W.
PLoS ONE7:E45088-E45088(2012) [PubMed] [Europe PMC] [Abstract]

"Human Bop is a novel BH3-only member of the Bcl-2 protein family."
Zhang X. , Weng C. , Li Y. , Wang X. , Jiang C. , Li X. , Xu Y. , Chen Q. , Pan L. , Tang H.
Protein Cell3:790-801(2012) [PubMed] [Europe PMC] [Abstract]

"Structural insights into the degradation of Mcl-1 induced by BH3 domains."
Czabotar P.E. , Lee E.F. , van Delft M.F. , Day C.L. , Smith B.J. , Huang D.C.S. , Fairlie W.D. , Hinds M.G. , Colman P.M.
Proc. Natl. Acad. Sci. U.S.A.104:6217-6222(2007) [PubMed] [Europe PMC] [Abstract]

"The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer."
Stewart M.L. , Fire E. , Keating A.E. , Walensky L.D.
Nat. Chem. Biol.6:595-601(2010) [PubMed] [Europe PMC] [Abstract]

"DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome."
Ley T.J. , Mardis E.R. , Ding L. , Fulton B. , McLellan M.D. , Chen K. , Dooling D. , Dunford-Shore B.H. , McGrath S. , Hickenbotham M. , Cook L. , Abbott R. , Larson D.E. , Koboldt D.C. , Pohl C. , Smith S. , Hawkins A. , Abbott S. , Locke D. , Hillier L.W. , Miner T. , Fulton L. , Magrini V. , Wylie T. , Glasscock J. , Conyers J. , Sander N. , Shi X. , Osborne J.R. , Minx P. , Gordon D. , Chinwalla A. , Zhao Y. , Ries R.E. , Payton J.E. , Westervelt P. , Tomasson M.H. , Watson M. , Baty J. , Ivanovich J. , Heath S. , Shannon W.D. , Nagarajan R. , Walter M.J. , Link D.C. , Graubert T.A. , DiPersio J.F. , Wilson R.K. more...
Nature456:66-72(2008) [PubMed] [Europe PMC] [Abstract]